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Physiological and histological alterations in laboratory rabbits infected with Necator americanus (Nematoda: Ancylostomatidae) | ||
Caspian Journal of Environmental Sciences | ||
مقالات آماده انتشار، اصلاح شده برای چاپ، انتشار آنلاین از تاریخ 05 اسفند 1402 اصل مقاله (923.37 K) | ||
نوع مقاله: Research Paper | ||
شناسه دیجیتال (DOI): 10.22124/cjes.2024.7601 | ||
نویسندگان | ||
Maroof Sabti Juma Al-Ammash* 1؛ Marwa Shakir Mahmood Al-Badry2؛ Salah Abed Hasan3 | ||
1Department of Pathological Analysis, Faculty of Applied Science, University of Samarra, Iraq | ||
2Department of Biology, Faculty of Education, University of Samarra, Iraq | ||
3Department of Biology, Faculty of Science, University of Sfax, Tunis | ||
چکیده | ||
The present study was conducted for the period from April to October 2022 in University of Samarra laboratories, Iraq. The study included 20 male laboratory rabbits, whose weight ranged from 1.4 to 1.5 kg, ten of them were as a control group and the other ten were infected with N. americanus parasite. Some biochemical tests were carried out such as lipid profile (HDL, Cholesterol, and Triglycerides) and liver enzymes (GOT and GPT), as well as tissue sections of the liver, lung and small intestine to see the alterations due to infection. The present results showed significant differences for total cholesterol between control and infected groups (88.40 and 71.80 mg dL-1, respectively). In the case of triglycerides, non-significant variances were recorded between control and infected groups (68.80 and 69.80 mg dL-1, respectively), whereas in the case of HDL, the present results showed significant differences between control and infected groups (27.40 and 22.60 mg dL-1, respectively). The current results showed significant increase in concentration of GOT of infected group compared to control group (27.20 and 15.60 mg dL-1, respectively). As for GPT, non-significant variances were recorded between infected and control groups (17.80 and 14.60 mg dL-1, respectively), while for Iron, significant differences occured between infected and control groups (74.00 and 101.40 mg dL-1 respectively). The histological study showed the presence of histological alterations in the members of infected group. | ||
کلیدواژهها | ||
Necator americanus؛ Rabbit؛ Physiology؛ Histology | ||
مراجع | ||
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