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Comparative study of the composition and biological activity of polyphenols of currants, raspberries and strawberries | ||
| Caspian Journal of Environmental Sciences | ||
| دوره 23، شماره 4، دی 2025، صفحه 903-910 اصل مقاله (795.31 K) | ||
| نوع مقاله: Research Paper | ||
| شناسه دیجیتال (DOI): 10.22124/cjes.2025.9207 | ||
| نویسندگان | ||
| Zhanar Botbayeva1؛ Gulzhan Assemova2؛ Botbayeva Madina2؛ Bissimbayeva Saliya3؛ Duissebekova Gulbanu2؛ Sarsenova Aigerim2؛ Moldasheva Elmira4؛ Ainur Zheldybayeva* 5 | ||
| 1Department "Technology and standardization", JSC "K. Kulazhanov kazakh university of technology and business», Astana, Kazakhstan | ||
| 2Department "Microbiology and virology named after Sh. Sarbasova”, NJSC "Medical University Astana”, Astana, Kazakhstan | ||
| 3Laboratory of the first city hospital, R. Koshkarbaev, Astana, Kazakhstan | ||
| 4Department of Chemistry and Chemical Technology, K. Zhubanov Aktobe Regional University, Aktobe, Kazakhstan | ||
| 5Department of Food Biotechnology, Almaty Technological University, Almaty, Kazakhstan | ||
| چکیده | ||
| Berry fruits are of great nutritional and medicinal importance due to their polyphenolic compounds. The current research provided a comparative study of the polyphenolic compounds and bioactive activities of three fruits, currants (grapes), raspberries and strawberries, cultivated in the Almaty region of Kazakhstan. Polyphenolic compounds were determined using high-performance liquid chromatography and antioxidant activity was determined using two assays, DPPH and FRAP, and also for the alpha-glucosidase and acetylcholinesterase enzyme inhibitory activities. Quantitative analysis indicated that there were significant differences in the polyphenolic profile of these fruits. Total polyphenol content in strawberry (520.6 mg g-1 dry weight) was significantly higher than raspberry (452.8) and currant (385.5). Strawberries had a very high content of this compound, i.e., 223 mg/100 g dry weight of anthocyanins. Raspberries, however, had the highest content of ellagitannins (158.4 mg/100 g dry weight) and had the highest DPPH free radical inhibitory activity (IC₅₀ value of 38.5 μg mL-1). Currants were also the richest in these compounds and had 1.151 mg/100 g dry weight of flavonols. In the enzyme inhibition test, raspberries were the most potent inhibitors of the enzymes alpha-glucosidase (IC₅₀ = 0.65 mg mL-1) and acetylcholinesterase (IC₅₀ = 1.15 mg mL-1). The results of this research clearly show that all these fruits possess a unique chemical fingerprint and hence have varying health-promoting potential, which can be utilized as a scientific basis for the development of targeted nutraceutical products. | ||
| کلیدواژهها | ||
| Polyphenols؛ Antioxidant activity؛ Enzyme inhibition؛ Strawberry؛ Raspberry | ||
| مراجع | ||
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