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| تعداد نشریات | 32 |
| تعداد شماره‌ها | 813 |
| تعداد مقالات | 7,859 |
| تعداد مشاهده مقاله | 35,870,321 |
| تعداد دریافت فایل اصل مقاله | 8,204,462 |
Medicinal plants in the management of environment-related diseases: Opportunities and challenges | ||
| Caspian Journal of Environmental Sciences | ||
| مقالات آماده انتشار، اصلاح شده برای چاپ، انتشار آنلاین از تاریخ 16 شهریور 1404 اصل مقاله (652.27 K) | ||
| نوع مقاله: Reviewers | ||
| شناسه دیجیتال (DOI): 10.22124/cjes.2025.9044 | ||
| نویسندگان | ||
| Shaira Atadjanova* 1؛ Kamoliddin Makhmudov2؛ Bekmurodjon Rakhimjonov2؛ Madina Abduraxmanova3؛ Shoyunus Obidov4؛ Munavvar Iskandarova5؛ Sardor Zubtiyev6؛ Firuza Maksudova7؛ Dildora Israilova8؛ Javokhir Mustaqimov9؛ Dilshod Esanov10؛ Mukhiddin Kosimov11؛ Uchkun Eshonkulov12 | ||
| 1Associate Professor, Andijan State Medical Institute, 1Yu.Atabekov Str., Andijan Region, Uzbekistan | ||
| 2Associate Professor of the Tashkent State Technical University, Uzbekistan | ||
| 3Doctor of Philosophy (PhD) in Technical Sciences, Tashkent Chemical-Technological Institute, Uzbekistan | ||
| 4Tashkent Institute of Chemical Technology, Uzbekistan | ||
| 5Doctoral Student, Tashkent State Technical University, Uzbekistan | ||
| 6Assistant of the Department of Pathological Anatomy, Tashkent State Medical University, Tashkent, Republic of Uzbekistan | ||
| 7DSc, Professor, Tashkent Pharmaceuticals Institute, Department of Industrial Technology of Medicines, Uzbekistan | ||
| 8Tashkent Institute of Irrigation and Agricultural Mechanization Engineers, National Research University, English Language Department, Teacher, Tashkent, Uzbekistan | ||
| 9Assistant, Department of Orthopaedic Dentistry and Orthodontics, Bukhara State Medical Institute, Bukhara City, Uzbekistan | ||
| 10Associate Assistant of the Department of Orthopaedic Dentistry and Orthodontics of the Bukhara State Medical Institute, Bukhara City, Uzbekistan | ||
| 11Doctor of Philosophy in Economics Science, Associate Professor of the Мining Department of the Almalyk Branch of the Scientific Research Technological University «MISIS» | ||
| 12PhD, Karshi State Technical University, Republic of Uzbekistan | ||
| چکیده | ||
| Environmental diseases pose a double threat—as such diseases affect the general population or affect only a very small segment of it-they continue to be recognized as one of the biggest health hazards in the world. Changes in respiratory disease, cardiovascular disease, cancer, and metabolic diseases all fall into this never-ending category. Diseases may be directly or indirectly caused by environmental pollution through mechanisms such as oxidative stress, inflammatory response, mitochondrial dysfunction, immune disturbance, or even epigenetic transformation. Medicinal plants and their phytochemicals offer the possibility of treatment since their actions on physiological systems are many and varied, have been proven to be safe at appropriate doses, and almost all have been used by humans practically since the beginning of civilization for medicine. This review will cover the mechanistic basis of phytochemicals counteracting pathological responses to toxicants, examples of their incorporation into pharmacy practice, and obstacles to their enabling actual use in clinical applications. | ||
| کلیدواژه‌ها | ||
| Plant؛ Environment؛ Toxins؛ Disease | ||
| مراجع | ||
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Afsharnezhad, M, Shahangian, SS, Panahi, E & Sariri, R 2017, Evaluation of the antioxidant activity of extracts from some fruit peels. Caspian Journal of Environmental Sciences, 15(3): 213–222.
Amanpour, P, Eftekhari, Z, Eidi, A & Khodarahmi, P 2024, Ameliorative mechanism of dietary vitamin d and magnesium on newborn’s pulmonary toxicity induced by cadmium. Journal of Trace Elements in Medicine and Biology: Organ of the Society for Minerals and Trace Elements (GMS), 84: 127469.
Barzi, NV, Eftekhari, Z, Doroud, D & Eidi, A 2020, DNA methylation changes of apoptotic genes in organogenesis stage of mice embryos by maternal chlorpyrifos induction. Environmental Toxicology, 35(7): 794-803.
Bisht, D, Kumar, Deepak, Kumar, Dharmendra, Dua, K & Chellappan, DK 2021, Phytochemistry and pharmacological activity of the genus Artemisia. Archives of pharmacal research, 44(5): 439-474.
Bolognesi, G, Bacalini, MG, Pirazzini, C, Garagnani, P & Giuliani, C 2022, Evolutionary Implications of Environmental Toxicant Exposure. Biomedicines, 10(12).
Checa, J & Aran, JM 2020, Reactive Oxygen Species: Drivers of Physiological and Pathological Processes. Journal of inflammation research, 13: 1057–1073.
F Martins, ML, Heydari, P, Li, W, Martínez-Chávez, A, Venekamp, N, Lebre, MC, Lucas, L, Beijnen, JH & Schinkel, AH 2022, Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites. Frontiers in pharmacology, 13: 855000.
Gheibi, P, Eftekhari, Z, Doroud, D & Parivar, K 2023, Association between uterine toxicity induced by chlorpyrifos and downregulation of heparin-binding epidermal growth factor and L-selectin genes.Veterinary research forum : an international quarterly journal, 14(1): 45–52.
Kumar, A, Siddiqi, NJ, Alrashood, ST, Khan, HA, Dubey, A & Sharma, B 2021, Protective effect of eugenol on hepatic inflammation and oxidative stress induced by cadmium in male rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 139:111588.
Lalehgani, H, Amini, A & Shakerin, H 2025, Effects of Zingiber officinale in complementary care for postoperative complications: A systematic review. Journal of Herbmed Pharmacology, 14(3):315–331.
Liew, KY, Hafiz, MF, Chong, YJ, Harith, HH, Israf, DA & Tham, CL 2020, A Review of Malaysian Herbal Plants and Their Active Constituents with Potential Therapeutic Applications in Sepsis. Evidence-Based Complementary and Alternative Medicine, 2020(1): 8257817, viewed <https://doi.org/10.1155/2020/8257817>.
Lin, Y, Zeng, H, Lin, J, Peng, Y, Que, X, Wang, L, Chen, L & Bai, N 2024, Evaluating the therapeutic potential of moxibustion on polycystic ovary syndrome: a rat model study on gut microbiota and metabolite interaction. Frontiers in Cellular and Infection Microbiology, 14: 1328741.
Luthra, R & Roy, A 2022, Role of Medicinal Plants against Neurodegenerative Diseases. Current Pharmaceutical Biotechnology, 23(1): 123–139.
Mardani-Nafchi, H, Rahimian, G, Amini, A & Baratpour, I 2025, A systematic review of polyphenols therapeutic and preventive role in cholelithiasis. Journal of Herbmed Pharmacology, 14(2): 120–132.
MARTINS, ASDAPAZ, DE CERQUEIRA ALVES, M, DE ARAÚJO, ORP, DOS SANTOS CAMATARI, FO, GOULART, MOF & MOURA, FA 2023, Curcumin in inflammatory bowel diseases: Cellular targets and molecular mechanisms. Biocell, 47(11): 2547–2566, viewed <https://www.sciencedirect.com/science/article/pii/ S0327954523000488>.
McCombe, JA & Pittock, SJ 2022, Anti-complement Agents for Autoimmune Neurological Disease. Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics, 19(3): 711–728.
Meyer, JN, Leuthner, TC & Luz, AL 2017, Mitochondrial fusion, fission, and mitochondrial toxicity. Toxicology, 391: 42–53.
Rattan, S, Zhou, C, Chiang, C, Mahalingam, S, Brehm, E & Flaws, JA 2017, Exposure to endocrine disruptors during adulthood: consequences for female fertility. The Journal of Endocrinology, 233(3): R109–R129.
Rudrapal, M, Rakshit, G, Singh, RP, Garse, S, Khan, J & Chakraborty, S 2024, Dietary polyphenols: review on chemistry/sources, bioavailability/metabolism, antioxidant effects, and their role in disease management. Antioxidants, 13(4): 429.
Shi, Q, Pei, F, Silverman, GA, Pak, SC, Perlmutter, DH, Liu, B & Bahar, I 2020, Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis. International journal of molecular sciences, 21(8).
Shimada, T 2006, Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons. Drug metabolism and pharmacokinetics, 21(4): 257–276.
Vahabi Barzi, N, Eftekhari, Z, Doroud, D & Eidi, A 2022, Maternal exposure during organogenesis to chlorpyrifos insecticide induce apoptosis process. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 35(20): 3845–3852.
Wu, D & Meydani, SN 2019, Antioxidants and immune function. Antioxidant Status, Diet, Nutrition, and Health, CRC Press,370–400.
Zhang, L, Xu, Z, Mak, JWY, Chow, KM, Lui, G, Li, TCM, Wong, CK, Chan, PKS, Ching, JYL, Fujiwara, Y, Chan, FKL & Ng, SC 2022, Gut microbiota-derived synbiotic formula (SIM01) as a novel adjuvant therapy for COVID-19: An open-label pilot study. Journal of gastroenterology and hepatology, 37(5): 823–831. | ||
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آمار تعداد مشاهده مقاله: 127 تعداد دریافت فایل اصل مقاله: 15 |
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