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Effects of sophoroflavonoside and narcissin flavonoids on the amount of malondialdehyde, a product of lipid peroxidation, and the activity of the enzyme cytochrome c oxidase in rat liver mitochondria poisoned with indoxacarb pesticide | ||
| Caspian Journal of Environmental Sciences | ||
| دوره 21، شماره 4، دی 2023، صفحه 997-1000 اصل مقاله (602.23 K) | ||
| شناسه دیجیتال (DOI): 10.22124/cjes.2023.7159 | ||
| نویسندگان | ||
| M.J. Parpieva1؛ P. Mirkhamidova2؛ M.K. Pozilov3؛ R.A. Alimova* 4 | ||
| 1Andijan State University, Andijan City | ||
| 2Tashkent State Pedagogical University Named after Nizomi, Tashkent City | ||
| 3M. Ulugbek National University of Uzbekistan, Tashkent City | ||
| 4Tashkent State Agrarian University, Tashkent City, Republic of Uzbekistan | ||
| چکیده | ||
| In this study, the effects of soforaflavonolonoside and narcissin flavonoids on the amount of malondialdehyde, a product of peroxidation of lipids in the liver mitochondria of rats poisoned with indoxacarb pesticide, and on the activity of the enzyme cytochrome-s-oxidase were studied depending on the dynamics of 10, 20, 30 and 40 days. The experimental group was injected with indoxacarb pesticide at a dose of 1/10 LD50 through a special probe. After administration of indoxacarb pesticide, animals were administered orally with soforaflavonolonoside and narcissin flavonoid at a dose of 10 mg kg-1 once a day for 10 days. | ||
| کلیدواژهها | ||
| Pesticide؛ Indoxacarb؛ saphoroflavonoside؛ Flavonoid؛ Saphoroflavonoside (SFL)؛ Narcissin؛ Lipid peroxidation (LPO) | ||
| مراجع | ||
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Mirkhamidova, P, Pozilov, MK, Parpieva, MJ, Shakhmurova, GA & Jumagulova KA 2022, Determination of the amount of residual pesticides in the liver tissue of rats poisoning with haloxyphop-r-methyl and indosacarb pesticides. Journal of Pharmaceutical Negative Results,13: 738-745
Mirkhamidova, P, Tuychieva, D, Bobokhonova, D & Parpieva, M 2020, Influence of karate on the activity of enzymes of the anti-oxidizing system of rat liver protection and ways of their correction. European Journal of Molecular & Clinical Medicine. 7: 3757-3765.
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