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The Optimizing Process of the Blood Coagulation Powder Composition With Response Surface Methodology | ||
| Computational Sciences and Engineering | ||
| دوره 2، شماره 2، آذر 2022، صفحه 311-322 اصل مقاله (858.72 K) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.22124/cse.2023.23925.1051 | ||
| نویسندگان | ||
| Reza Zarei* 1؛ Seyyedeh Sahra Mirmasoudi2؛ Alireza Feizkhah3؛ Zahra Pourmohammadi Bejarpasi4؛ Mohsen Shahrousvand5 | ||
| 1Department of Statistics, Faculty of Mathematical Sciences, University of Guilan, Rasht, Iran. | ||
| 2Burn and Regenerative Medicine Research center, Guilan University of Medical Sciences, Rasht | ||
| 3Department of Medical Physics, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran | ||
| 4Burn and Regenerative Medicine Research center, Guilan University of Medical Sciences, Rasht, Iran | ||
| 5Caspian Faculty of Engineering, College of Engineering, University of Tehran, Tehran, Iran | ||
| چکیده | ||
| This study focuses on optimizing process of the blood coagulation powder composition with response surface methodology. For this purpose, optimizing the synthesis conditions of powder composition, the response surface methodology (RSM) was used by Box-Behnken design (BBD). The variables of this method were sodium alginate (A) and zinc oxide nanoparticles (B), prepared in combination with a fixed percentage of shell powder and measured for different reactions. results showed that according to the response surface methodology, which is the most optimal case, to introduce this method as a suitable suggestion for this kind of problem in the applications of vascular surgeries, burns, etc., and direct to future pre-clinic and clinical studies. | ||
| کلیدواژه‌ها | ||
| RSM؛ Coagulation powder؛ Box-Behnken design | ||
| مراجع | ||
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